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Scientific Papers and Reviews
 

Selected Publications

Click on the title in purple of any paper listed to go to the abstract of the paper on PubMed.
Note that only the titles in purple are hyperlinked to publications.

2006


Sekine K, Revzin A, Tompkins RG, Toner M.
Panning of multiple subsets of leukocytes on antibody-decorated poly(ethylene)
glycol-coated glass slides

J Immunol Methods. 2006 Jun 30;313(1-2):96-109. Epub 2006 Jun 8.
PMID: 16822521 [PubMed - in process]

Kane BJ, Zinner MJ, Yarmush ML, Toner M.
Liver-specific functional studies in a microfluidic array of primary mammalian hepatocytes
Anal Chem. 2006 Jul 1;78(13):4291-8.
PMID: 16808435 [PubMed - in process]

Murthy SK, Sethu P, Vunjak-Novakovic G, Toner M, Radisic M.
Size-based microfluidic enrichment of neonatal rat cardiac cell populations
Biomed Microdevices. 2006 May 19; [Epub ahead of print]
PMID: 16732418 [PubMed - as supplied by publisher]

Pregibon DC, Toner M, Doyle PS.
Magnetically and biologically active bead-patterned hydrogels
Langmuir. 2006 May 23;22(11):5122-8.
PMID: 16700603 [PubMed - in process]

Irimia D, Geba DA, Toner M.
Universal microfluidic gradient generator
Anal Chem. 2006 May 15;78(10):3472-7.
PMID: 16689552 [PubMed - in process]

Irimia D, Toner M.
Cell handling using microstructured membranes
Lab Chip. 2006 Mar;6(3):345-52. Epub 2006 Feb 8.
PMID: 16511616 [PubMed - indexed for MEDLINE]

Irimia D, Liu SY, Tharp WG, Samadani A, Toner M, Poznansky MC.
Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients
Lab Chip. 2006 Feb;6(2):191-8. Epub 2005 Dec 23.
PMID: 16450027 [PubMed - indexed for MEDLINE]

2005

Sethu P, Sin A, Toner M.
Microfluidic diffusive filter for apheresis (leukapheresis)
Lab Chip. 2006 Jan;6(1):83-9. Epub 2005 Nov 11.
PMID: 16372073 [PubMed - indexed for MEDLINE]

Tharp WG, Yadav R, Irimia D, Upadhyaya A, Samadani A, Hurtado O, Liu SY, Munisamy S, Brainard DM, Mahon MJ, Nourshargh S, van Oudenaarden A, Toner MG, Poznansky MC.
Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo
J Leukoc Biol. 2006 Mar;79(3):539-54. Epub 2005 Dec 19.
PMID: 16365152 [PubMed - indexed for MEDLINE]

Sin A, Murthy SK, Revzin A, Tompkins RG, Toner M.
Enrichment using antibody-coated microfluidic chambers in shear flow: model mixtures of human lymphocytes
Biotechnol Bioeng. 2005 Sep 30;91(7):816-26.
PMID: 16037988 [PubMed - indexed for MEDLINE]

Toner M, Irimia D.
Blood on a Chip

Annu Rev Biomed Eng. 2005 Aug 15;7:77-103.
PMID: 16004567 [PubMed - as supplied by publisher]

Downing BR, Cornwell K, Toner M, Pins GD.
The influence of microtextured basal lamina analog topography on keratinocyte function and epidermal organization

J Biomed Mater Res A. 2005 Jan 1;72(1):47-56.
PMID: 15543632 [PubMed - indexed for MEDLINE]

Murthy SK, Sin A, Tompkins RG, Toner M.
Effect of flow and surface conditions on human lymphocyte isolation using microfluidic chambers

Langmuir. 2004 Dec 21;20(26):11649-55.
PMID: 15595794
Park J, Berthiaume F, Toner M, Yarmush ML, Tilles AW.
Microfabricated grooved substrates as platforms for bioartificial liver reactors

Biotechnol Bioeng. 2005 Jun 5;90(5):632-44.
PMID: 15834948

Revzin A, Sekine K, Sin A, Tompkins RG, Toner M.
Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes

Lab Chip. 2005 Jan;5(1):30-7. Epub 2004 Oct 12.
PMID: 15616737 [PubMed - indexed for MEDLINE]

2004


Revzin A, Rajagopalan P, Tilles AW, Berthiaume F, Yarmush ML, Toner M.
Designing a hepatocellular microenvironment with protein microarraying and poly(ethylene glycol) photolithography

Langmuir. 2004 Apr 13;20(8):2999-3005. No abstract available.
PMID: 15875819

Chan C, Berthiaume F, Nath BD, Tilles AW, Toner M, Yarmush ML.
Hepatic tissue engineering for adjunct and temporary liver support

Liver Transplantation 2004; 10: 1331-1342

Irimia D, Tompkins RG, Toner M.
Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device

Anal Chem. 2004 Oct 15;76(20):6137-43.
PMID: 15481964

Liz Z, Yarmush ML, Chan C.
Insulin concentration during preconditioning mediates the regulation of urea synthesis during amino-acid supplemented plasma

Tissue Engineering 2004; 10: 1737-1746.

Murthy, S. K.; Sin, A.; Tompkins, R. G.; Toner, M.;
Effect of Flow and Surface Conditions on Human Lymphocyte Isolation Using Microfluidic Chambers

Langmuir 20(26); 11649-11655.

Revzin A, Sekine K, Sin A, Tompkins RG, Toner M.
Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes

Lab-on-a-Chip 2004; 5(1): 30-37.

Sethu P, Anahtar M, Moldawer LL, Tompkins RG, Toner M.
Continuous flow microfluidic device for rapid erythrocyte lysis

Anal Chem. 2004 Nov 1;76(21):6247-53.
PMID: 15516115

Thompson DM, King KR, Wieder KJ, Toner M, Yarmush ML, Jayaraman A.
Dynamic gene expression profiling using a microfabricated living cell array

Anal Chem. 2004 Jul 15;76(14):4098-103.
PMID: 15253648 [PubMed - indexed for MEDLINE]

2003


Maxwell RB, Gerhardt AL, Toner M, Gray ML, Schmidt MA. 2003.
A microbubble-powered bioparticle actuator

Journal of Microelectromechanical Systems 12(5):630-640.

Revzin A, Tompkins RG, Toner M. 2003.
Surface engineering with poly(ethylene glycol) photolithography to create high-density cell arrays on glass

Langmuir 19(23):9855-9862.

Voldman J, Toner M, Gray ML, Schmidt M.
Design and analysis of extruded quadrupolar dielectrophoretic traps

Journal of Electrostatics 2003; 57: 69-90.

2002


Li Jeon N, Baskaran H, Dertinger SK, Whitesides GM, Van de Water L, Toner M.
Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device

Nat Biotechnol. 2002 Aug;20(8):826-30. Epub 2002 Jul 1.
PMID: 12091913 [PubMed - indexed for MEDLINE]

Voldman J, Gray ML, Toner M, Schmidt MA.
A microfabrication-based dynamic array cytometer

Anal Chem. 2002 Aug 15;74(16):3984-90.
PMID: 12199564 [PubMed - indexed for MEDLINE]

2001

Tilles AW, Baskaran H, Roy P, Yarmush ML, Toner M.
Effects of oxygenation and flow on the viability and function of rat hepatocytes cocultured in a microchannel flat-plate bioreactor

Biotechnol Bioeng. 2001 Jun 5;73(5):379-89.
PMID: 11320508 [PubMed - indexed for MEDLINE]

Roy P, Baskaran H, Tilles AW, Yarmush ML, Toner M.
Analysis of oxygen transport to hepatocytes in a flat-plate microchannel bioreactor

Ann Biomed Eng. 2001 Nov;29(11):947-55.
PMID: 11791677 [PubMed - indexed for MEDLINE]

Roy P, Washizu J, Tilles AW, Yarmush ML, Toner M.
Effect of flow on the detoxification function of rat hepatocytes in a bioartificial liver reactor

Cell Transplantation 2001; 10: 609-614.

Voldman J, Braff RA, Toner M, Gray ML, Schmidt MA.
Holding forces of single-particle dielectrophoretic traps

Biophys J. 2001 Jan;80(1):531-41.
PMID: 11159423 [PubMed - indexed for MEDLINE]

Shito M, Kim NH, Baskaran H, Tilles AW, Tompkins RG, Yarmush ML, Toner M.
In vitro and in vivo evaluation of albumin synthesis rate of porcine hepatocytes in a flat-plate bioreactor

Artif Organs. 2001 Jul;25(7):571-8.
PMID: 11493279 [PubMed - indexed for MEDLINE]

2000

Folch A, Toner M.
Microengineering of cellular interactions

Annu Rev Biomed Eng. 2000;2:227-56. Review.
PMID: 11701512 [PubMed - indexed for MEDLINE]

Tilles AW, Classen JM, Toner M, Van De Water L.
Simple devices to facilitate the analysis of collagen contraction by cells

Biotechniques. 2000 Sep;29(3):412-4, 416, 418. No abstract available.
PMID: 10997250 [PubMed - indexed for MEDLINE]

Folch. A, Mezzour S, During M, Hurtado O, Toner M, Muller R.
Stacks of microfabricated structures as scaffolds for cell culture and tissue engineering

J. Biomed. Microdevices 2000; 2: 3-10.

Folch A, Jo BH, Hurtado O, Beebe DJ, Toner M.
Microfabricated elastomeric stencils for micropatterning cell cultures

J Biomed Mater Res. 2000 Nov;52(2):346-53.
PMID: 10951374 [PubMed - indexed for MEDLINE]

Pins GD, Toner M, Morgan JR.
Microfabrication of an analog of the basal lamina: biocompatible membranes with complex topographies

FASEB J. 2000 Mar;14(3):593-602.
PMID: 10698975 [PubMed - indexed for MEDLINE]

Voldman J, Gray M, Schmidt MA.
An Integrated Liquid Mixer/Valve

Microelectromechanical Systems J. 2000, Vol. 9, No. 3, 295-302.

1999

Bhatia SN, Balis UJ, Yarmush ML, Toner M.
Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells

FASEB J. 1999 Nov;13(14):1883-900. Review.
PMID: 10544172 [PubMed - indexed for MEDLINE]

Folch A, Ayon A, Hurtado O, Schmidt MA, Toner M.
Molding of deep polydimethylsiloxane microstructures for microfluidics and biological applications

J Biomech Eng. 1999 Feb;121(1):28-34.
PMID: 10080086 [PubMed - indexed for MEDLINE]

Ledezma GA, Folch A, Bhatia SN, Balis UJ, Yarmush ML, Toner M.
Numerical model of fluid flow and oxygen transport in a radial-flow microchannel containing hepatocytes

J Biomech Eng. 1999 Feb;121(1):58-64.
PMID: 10080090 [PubMed - indexed for MEDLINE]

1998

Bhatia SN, Balis UJ, Yarmush ML, Toner M.
Probing heterotypic cell interactions: hepatocyte function in microfabricated co-cultures

J Biomater Sci Polym Ed. 1998;9(11):1137-60.
PMID: 9860177 [PubMed - indexed for MEDLINE]

Bhatia SN, Balis UJ, Yarmush ML, Toner M.
Microfabrication of hepatocyte/fibroblast co-cultures: role of homotypic cell interactions

Biotechnol Prog. 1998 May-Jun;14(3):378-87.
PMID: 9622518 [PubMed - indexed for MEDLINE]

Folch A, Toner M. Cellular micropatterns on biocompatible materials
Biotechnol Prog. 1998 May-Jun;14(3):388-92.
PMID: 9622519 [PubMed - indexed for MEDLINE]

1997


Bhatia SN, Yarmush ML, Toner M.
Controlling cell interactions by micropatterning in co-cultures: hepatocytes and 3T3 fibroblasts

J Biomed Mater Res. 1997 Feb;34(2):189-99.
PMID: 9029299 [PubMed - indexed for MEDLINE]

1994


Bhatia SN, Toner M, Tompkins RG, Yarmush ML.
Selective adhesion of hepatocytes on patterned surfaces

Ann N Y Acad Sci. 1994 Nov 30;745:187-209.
PMID: 7832508

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